28 дек 2004 г. - Cannabis and KYNA
Описание:
Exogenous cannabinoids such as cannabidiol or Δ9-tetrahydrocannabinol are known to stimulate IDO enzyme activity in dependence of cannabinoid receptor activation [120]. This stimulation, together with the pharmacological inhibition of the kynurenine 3-monooxygenase (KMO) enzyme [123] may enhance endogenous KYNA levels indirectly, through the kynurenine pathway, which will result in an enhanced reduction in NMDA receptor activity via the antagonizing effect of KYNA.
Добавлено на ленту времени:
New timeline
Дата:
