feb 22, 1495 - King Charles VIII of France enters Naples, to claim the city's throne. A few months later, he decides to return to France, and leaves Naples with most of his army, leaving a force under his cousin Gilbert, Count of Montpensier as viceroy. Syphilis is first definitely recorded in Europe during this invasion.[1] (perhaps from French forces who may have contacted Croats fleeing an Ottoman army in the east)