jan 1, 1525 - Charles V (HRE) defeats French army at Pavia Italy and captures Francis I of France
Francis I forced to renounce all claims to Italian territory to gain his freedom, but furiously repudiated the treaty the moment he reached France, reigniting the conflict.
Added to timeline:
Chapter 14 p. 461-471 Timeline
Habsburg and Valois Dynastic Struggles and influences