Artificial embryo twinning in a vertebrate (jan 1, 1902 – dec 31, 1902)
Description:
Spemann tried to figure out how to split two cells of an embryo much stickier than sea urchin cells. Spemann fashioned a tiny noose and tightened it between two cells of a salamander embryo until they separated. Each cell grew into an adult salamander. This experiment showed that embryos from a more-complex animal can also be “twinned” to form multiple identical organisms—but only up to a certain stage in development.
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