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NBL TME

Created by Jaime

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Events

Notification of Award Decision Begin Aim 1a Begin Aim 1b Begin Aim 2 Send samples for Illumina Sequencing Funding end date

Periods

Grow up NBL cell lines MDs to collect primary NBL and BM metastases samples NBL cell line xenograft experiments (+/- CXCL12, SCF and GM-CSF)Knock out CXCR4 with CRISPR-Cas9 NBL cell line xenograft experiments (+/- CXCR4)NBL primary and BM metastases xenograft experiments In vitro experiments to establish proper sgRNA expression Xenograft NBL cells expressing sgRNA library Analysis of sequencing results Manuscript preparation

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