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The First Crusade
One of the major publications of Renaissance natural philosophy - Epitome of Ptolemy's Almagest
Publication of the highly influential Corpus Hermeticum
Georg Peurbach's New Theory of the Planets
The Malleus Malificarum (The Hammer of the Witches) is published
Giovanni Pico della Mirandola attacks 'practical magic', especially, astrology, as it calls into questions traditional notions of human free will
The London College of Physicians is granted a royal charter and functions both as a traditional professional guild as well as a learned society
Ferdinand Magellan famously completes the first circumnavigation of the globe.
Girolamo Fracastoro provides one of the first descriptions of a new disease titled, Syphilis, or the French Disease.
1530- 1536 Publication of Portraits of Living Plants, by Otto Brunfels's, a botanical work that included illustrations from living plants
Juan Luis Vives in his On the Disciplines argues for the reform of education and a more receptive approach to skills traditionally associated with the craft and trade traditions.
Peter Apian and Fracastoro observe that the tail of the comet pointed away from the sun
In mathematics, Girolamo Cardano's, The Great Art contained many algebraic innovations and new methods for treating equations of the third degree
Newton's Observations Upon the Prophecies is published
Newton publishes second English edition of Opticks
The comet that now bears Edmond Halley's name is determined by him to have an elongated elliptical orbit, and therefore argued it should submit to Newtonian principles.
Isaac Newton publishes the first edition of his Opticks, including a series of speculations about nature and natural philosophy
Gottfried Wilhelm von Leibniz organizes and establishes the Berlin Academy of Science.
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