23
/
en
AIzaSyAYiBZKx7MnpbEhh9jyipgxe19OcubqV5w
January 31, 2020
Create
Public Timelines
Library
FAQ
For education
Cabinet
For educational institutions
For teachers
For students/pupils
Download
Export
Duplicate
Embed
Edit
29 views
0
0
Melanoma
Created by
Bart Chumbley
⟶ Updated 1 months ago ⟶
List of edits
Comments
Events
Hippocrates describes first melanoma; "melas" + "oma"
John Hunter removes the first melanoma, describing it as an “cancerous fungous excrescence.”
Rene Laenec first distinguished melanoma as a separate disease
William Norris first described the heterogeneous nature of melanoma tumors and recommended WIDE EXCISION
Sir Robert Carswell introduced the term "melanoma"
Herbert Lumley Snow started suggesting lymphadenectomy as "traps" for travelling cancer
Up to here, mainstay of treatment was wide excision, 5cm of normal skin and all subcutaneous material. Research into immune systems role underway.
Wallace Clark classified melanoma into three types and correlated depth of invasion inversely with prognosis
Breslow develops a scale of thickness and correlation to prognosis
Morton and colleagues begin using lymphoscintigraphy to resect relevant lymph node beds
Chemotherapy is being used to alternatively treat melanoma
Immunotherapy (IL-2) begins to be used to treat melanoma
