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DNA Timeline- Anabelle Kim - 1st hour
Important people that contributed to the discovery of information about DNA
1 Dec 2017
Erwin Chargaff discovered that guanine units equal the number of cytosine units and the number of adenine units equals the number of thymine units. He also discovered that the relative amounts of A, G, T, and C varied from species to species.
Oswald Avery was one of the first molecular microbiologists, however, he is mostly known for conducting an experiment that broke down DNA in heat-killed bacteria. He discovered that chromosomes and genes are made up of DNA.
Frederick Griffith conducted an experiment, that would later inspire Avery's experiment. Griffith discovered that heat-killed, disease-causing bacteria have a factor that can transform harmless bacteria into a disease.
Alfred Hershey and Martha Chase studied bacteriophage. They are known for conducting their famous Hersey-Chase experiment. They discovered that phage DNA was not a protein, but genetic material.
Rosalind Franklin is known for discovering that the structure of DNA is similar to a twisted ladder. She discovered this by using a technique called x-ray crystallography.
James Watson and Frances Crick were credited with discovering the double helix structure of the DNA molecule. Watson, Crick, along with another scientist Maurice Wilkins, received a noble prize.
Matthew Meselson and Franklin Stahl are known for conducting the Meselson–Stahl experiment. The experiment proved Watson and Crick's theory that DNA replication was semiconservative. Their experiment has been called "the most beautiful experiment in biology."
Gregor Mendel discovered the fundamental laws of inheritance through his experiment with pea plants. He disovered the law of segregation, the law of independent assortment, and the law of dominance.
Thomas H. Morgan is credited with discovering the chromosomal theory of inheritance. His experiment with fruit flies demonstrated sex-linked inheritance patterns.
Reiji Okazaki discovered that the lagging strand of DNA is replicated by fragments, later known as Okazaki fragments.
Reginald Punnett is known for the discovery of the Punnett square, which calculates the number and variety of genetic combinations. Punnett along with William Bateson discovered gene linkage, otherwise known as coupling.
Walther Flemming was the first person to describe the chromosomal movements in mitosis. He saw that chromosomes doubled in prophase and divided in cytokinesis.
Nettie Maria Stevens was one of the first female scientists to be famous in biological sciences. She discovered that specific chromosomes determine gender.
Alfred Sturtevant was a student of Thomas Hunt Morgan. Sturtevant discovered that genes get shuffled when chromosomes exchange pieces. He published the worlds first genetic map.
Charles Robert Darwin was known for discovering Darwinism or evolution. He discovered that evolution began the inheritance of a gene variation.
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