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June 15, 2020
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cell science
description words
Created by
krista
⟶ Updated 30 Oct 2017 ⟶
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Timelines by
krista
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30 Oct 2017
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Krista
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Events
Jansen invents microscope
Hooke discovered cells
Leeuwenhoek discovered protozoa and bacteria 9 years later
Brown described the cell nucleus
Schleiden and Schwann proposed cell theory
Albrecht von Roelliker discovered sperm cells and egg cells are cells
N. Pringsheim discovered how a sperm cell penetrated an egg cell
Rudolph Virchow discovers cells come from existing cells
Kolliker described mitochondria
Flemming described chromosome behavior during mitosis
Germ cells are haploid, chromosome theory of heredity
Golgi described the golgi apparatus
Behrens used differential centrifugation to separate nuclei from cytoplasm
Siemens produced the first commercial transmission electron microscope
Gey and coworkers established a continuous human cell line
Eagle systematically defined the nutritional needs of animal cells in culture
Meselson, Stahl and Vinograd developed density gradient centrifugation in cesium chloride solutions for separating nucleic acids
Ham introduced a defined serum-free medium. Cambridge Instruments produced the first commercial scanning electron microscope
Sato and colleagues publish papers showing that different cell lines require different mixtures of hormones and growth factors in serum-free media
Transgenic mice and fruit flies are produced. Mouse embryonic stem cell line established
Tsien identifies mutant of GFP with enhanced spectral properties
Mice are cloned from somatic cells
Hamilton and Baulcombe discover siRNA as part of post-transcriptional gene silencing in plants
