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30 Oct 2017
Robert Hooke discovered "cells" in cork
Jansen credited with 1st compound microscope
Leeuwenhoek discovered protozoa; he saw bacteria some 9 years later
Brown described the cell nucleus in the cells of a n orchard
Schleiden and Schwann proposed cell theory
Albrecht Von Roelliker he realized that sperm cells and egg cells are also cells
N. Pringsheim observed how a sperm cells penitrated an egg cell
Rudolf Virchow; he is a physician, pathologist, and anthropogist. He expounds his famous conclusion: omnis cellula e cellula (the cells develope only from existing cells)
Kolliker discribed mitrocondria
Flemming discribed chromosome behavior during mitosis.
Germ cells are haploid chromosome theory of heredity
Golgi discribed golgi apparatus
Behavior is used differential centrifgation to seperate the nucleus from cytoplasm
Gey and coworkers established a continuous human cell line.
Eagle systematically defined the nutritional needs of animal cells in culture.
Meselson, Stahl and Vinograd developed density gradient centrifugation in cesium chloride solutions for separating nucleic acids.
Ham introduced a defined serum-free medium. Cambridge Instruments produced the first commercial scanning electron microscope.
Sato and colleagues publish papers showing that different cell lines require different mixtures of hormones and growth factors in serum-free media.
Transgenic mice and fruit flies are produced. Mouse embryonic stem cell line established.
Tsien identifies mutant of GFP with enhanced spectral properties
Mice are cloned from somatic cells.
Hamilton and Baulcombe discover siRNA as part of post-transcriptional gene silencing (PTGS) in plants
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