May 31, 2020
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Ashton B. Crandall
⟶ Updated 31 Oct 2017 ⟶
List of edits
Ashton B. Crandall
8 Dec 2017
Jansen credited with 1st compound microscope
Hooke described ‘cells’ in cork.
Leeuwenhoek discovered protozoa. He saw bacteria some 9 years later.
Brown descibed the cell nucleus in cells of the orchid
Schleiden and Schwann proposed cell theory.
Albrecht von Roelliker realized that sperm cells and egg cells are also cells.
N. Pringsheim observed how a sperm cell penetrated an egg cell.
Rudolf Virchow (physician, pathologist and anthropologist) expounds his famous conclusion: omnis cellula e cellula, that is cells develop only from existing cells [cells come from preexisting cells]
Kolliker described mitochondria
Flemming described chromosome behavior during mitosis.
Germ cells are haploid, chromosome theory of heredity.
Golgi described the golgi apparatus.
Behrens used differential centrifugation to separate nuclei from cytoplasm.
Siemens produced the first commercial transmission electron microscope.
Gey and coworkers established a continuous human cell line.
Eagle systematically defined the nutritional needs of animal cells in culture.
Meselson, Stahl and Vinograd developed density gradient centrifugation in cesium chloride solutions for separating nucleic acids.
Ham introduced a defined serum-free medium. Cambridge Instruments produced the first commercial scanning electron microscope.
Transgenic mice and fruit flies are produced. Mouse embryonic stem cell line established.
Tsien identifies mutant of GFP with enhanced spectral properties.
Mice are cloned from somatic cells.
Hamilton and Baulcombe discover siRNA as part of post-transcriptional gene silencing (PTGS) in plants
Robert Hooke Born in Freshwater, United Kingdom Died in London, United Kingdom Hooke's law; Microscopy; Coining the word 'cell'
Anton van Leeuwenhoek Born: Delft, Netherlands and died in Delft, Netherlands. Van Leeuwenhoek discovered protozoa - the single-celled organisms and he called them "animalcules".
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