YO
Category: History
Updated: 1 days ago
anti-yo encephalomyelo-radiculitis
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Created byAndrea Porsio
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Sympton onset:
vertigo, nausea, and asthenia
after travel in RwandaFirst Brain MRI:
cerebellar T2/FLAIR hyperintensityAdmission in our Department1° CSF examination:
12 leucocytes/µL
All T-cell lymphocytes
No clonality
Proteins 0.86 g/L
NfL 48,047 pg/mL
OcB+
Anti-yo positivity: both CSF
and serum2° CSF examination:
16 leucocytes/µL
All T-cell lymphocytes
No clonality
Proteins 0.83 g/L3° CSF examination:
86 leucocytes/µL,
All T-cell lymphocytes
No clonality
Proteins 1.19 g/L
NfL 27,212 pg/mLSpine MRI: LETM and spinal
nerve roots contrast enhancementTotal hysterectomy with bilateral adnexectomy,
omentectomy, and peritoneal biopsiesOophorectomy ⇨ histology confirms
high grade ovarian serous carcinomaPeriods
High dosage steroid therapyClnical deteriorationIVIGSubacute progressive
spastic paraparesisHigh dosage steroid therapySubacute worsening
with III grade down-
beating nystagmus
and ataxiaNegative extended oncology screening
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