mar 1, 541 - Plague of Justinian

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The Plague of Justinian, also named after the Byzantine Emperor Justinian I, emerged as one of the first recorded pandemics in history. The outbreak is caused by the Yersinia pestis bacterium, the same pathogen responsible for the later Black Death. Causing an estimated 25 million deaths in the Mediterranean and Middle East, this event had profound effects on the population and economy of the affected regions.

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