jan 1, 1521 - Juan Ponce de Leon died

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In February 1521, Ponce de León left Puerto Rico for a second exploration of Florida. Records are scarce, but some accounts describe a poorly organized trip. The expedition landed somewhere on the western side of the Florida peninsula, where it was soon attacked by Calusa warriors. Ponce de León was wounded in the confrontation, possibly by a poison arrow to his thigh. The expedition sailed back to Cuba, where he died in July 1521.

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