may 1, 2005 - [CRISPR] Cas9 and PAM discovered (May 2005) -discovery made by Alexander Bolotin while studying the bacteria Streptococcus thermophilus -(Cas9-protospacer adjacent motif) a novel cas gene that encodes for a large protein predicted to have nuclease activity -(PAM) a sequence required for target recognition

The CRISPR System

14 Dec 2018

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may 1, 2005

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~ 20 years ago

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