4h 33min, jul 30, 1334 y - Black Plague occurs in Hubei, China
Description:
This epidemic would eventually kill over 90% of the population in Hubei as well as 5 million in China. Since As China was controlled by the Mongols, who heavily promoted trade, its spread westward was almost inevitabley.
Added to timeline:
Date:
4h 33min, jul 30, 1334 y
Now
~ 691 years ago