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feb 1, 2009 - THe gene encoding the Hhip is transcriptionally silenced by CpG island promoter hypermethylation in 26% of HB cases. Treatmnet with DNA-demethylating agent partially restored HHIP expression.

Description:

Blocking the hedgehog pathway inhibits hepatoblastoma growth.

Added to timeline:

BIOM3200 Project

ByFran
3 Oct 2018
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318

Date:

feb 1, 2009
Now
~ 17 years ago
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