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oct 5, 2007 - Reduced expression of HHIP in most GI cancer cell lines and in a certain subset of cancer tissues which correlated with promoter hypermethylation. Overexpression HHIP in some with correlation between expression levels and SHH, Indian hedgehog, Patched and GLI-1

Description:

Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer.

Added to timeline:

3 Oct 2018
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Date:

oct 5, 2007
Now
~ 18 years ago