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apr 26, 2016 - HHIP found to be epigenetically silenced in lung adenocarcinomas. Overexpression of HHIP blocked HH activation - suggests silencing of HHIP is critical in potentiating HH activation and maintaining cell survival under stress conditions.

Description:

Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma.

Added to timeline:

3 Oct 2018
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Date:

apr 26, 2016
Now
~ 9 years and 5 months ago