1 янв 1948 г. - Discovering the Parasite in Human Tissue

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"The third piece of the human malaria puzzle—where sporozoites inoculated by mosquitoes undergo early development in the human host—was solved in 1948. Although previous researchers had found that bird malaria initially reproduced in tissues of the lymph system and the bone marrow, the sanctuary for primate and human malaria outside of red blood cells remained a mystery. Then H. E. Shortt, P. C. C. Garnham, and colleagues at the Ross Institute of the London School of Hygiene and Tropical Medicine detected malaria parasites in the livers of rhesus monkeys infected with a primate malaria species. They subsequently found similar stages in liver biopsy specimens from human volunteers experimentally infected with P. vivax, and confirmed the same early sanctuary for P. falciparum (Garnham, 1966)." (Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance., n.d.)

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