1 gen 2223 anni - NIH: Study in rodents found acute inflammation in tracheal tissue, edema in lungs,

Descrizione:

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Conclusions:
In this sample, emissions from sugar cane burning induced acute focal and diffuse inflammation in ... tracheal tissues, with no loss of ciliated epithelial tissue. In the lung parenchyma of the animals in the experimental groups, there was interstitial and alveolar edema, together with polymorphonuclear cell infiltrates.

Sugar cane combustion releases a large quantity of particulate matter in addition to gases, such as ozone, carbon monoxide, nitric oxide, sulfur oxide, formaldehyde, benzopyrene, and polycyclic aromatic hydrocarbons, 6 - 8 all of which contribute to air pollution and adversely affect human health. 2 , 9 , 10

The particulates and toxic compounds generated by sugar cane burning are harmful to the respiratory tract, because as they are inhaled and deposited in the lower airways, they are ingested by a special type of white blood cells, which release an immune system cellular reaction, thus inducing inflammation. 4 , 8 The stress caused by smoke can trigger a series of cellular reactions that aim to restore stability; however, when this stress is chronic, it causes irreversible cellular damage. 11 Coarse particulates from smoke damages the upper airways, which are directly exposed to the external environment, whereas fine PM from smoke accumulates in the bronchi and bronchioles, leading to permanent damage and fibrosis. 12 , 13 Alveolar structures are susceptible to responses of an inflammatory nature and can cause pathological reactions with obstructive and restrictive consequences, 11 , 12 , 14 - 16 generally associated with the process of tissue remodeling. 14

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