14 magg 1996 anni - Nuclear transfer from laboratory cells

Descrizione:

Sheep
Ian Wilmut and Keith Campbell

All previous cloning experiments used donor nuclei from cells in early embryos. In this experiment, the donor nuclei came from a slightly different source: cultured sheep cells, which were kept alive in the laboratory.

Wilmut and Campbell transferred the nuclei from cultured cells into enucleated sheep egg cells. The lambs born from this procedure were named Megan and Morag.

This experiment showed that cultured cells can supply donor nuclei for cloning by nuclear transfer. Because scientists had already learned how to transfer genes into cultured cells, this experiment showed that it might be possible to use such modified cells to create transgenic animals—such as cows that could make insulin for diabetics in their milk.

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