23 sett 2017 anni - First time a base editor is used to edit DNA of embryos
Location: Sun Yat-Sen University, China
Method: Base editor
Journal: Protein & Cell
Type of embryo:
Disease treated: beta thalassemia
Results: Efficiency was 7-25.9%. Most of the edited embryos were mosaics,
with percentage of repaired cells being 20-75%. No off-target effects were found,
but only the “top 10 potential off-target sites” were analysed, so there could have
been unintended edits in the unexamined parts of the genome.
Aggiunto al nastro di tempo:
Gene editing
Data:
