24 nov 1749 año - The Province of South Carolina House of Assembly votes to free African-American slave Caesar Norman, and to grant him a lifetime pension of 100 British pounds per year, in return for Caesar's agreement to share the secret of his antidote for poisonous snake venom. Caesar then makes public his herbal cure of juice from Plantago major (the common plantain) and Marrubium vulgare (horehound), combined with "a leaf of good tobacco moistened with rum" (Cinta de tiempo)