1 ene 1903 año - Barbital

Descripción:

Created from the innocuous, prior-discovered barbituric acid, credit for which going to Adolf von Baeyer c. 1864, Barbital was the first of a giant of a class of drugs: the barbiturates. Inducted by Emil Fischer and Josef von Mering, a German chemist and physicist respectively, into medical utility in 1903 as a drug to promote sleep and stop seizures, barbital had a 9-year long heyday before being phased out by its cousin, phenobarbital, the oldest antiepileptic drug still prescribed and administered. The barbiturate class itself has plenty of such useful compounds for dealing with anxiety, epilepsy, insomnia, and otherwise, though only a tiny fraction compared to the 2,500-plus derived compounds of barbituric acid that aren’t used in humans. It took the induction of another entirely new class of drugs, the benzodiazepines, after over 30 years of timely successes, to knock the barbiturate family off its high-horse. Replacing barbiturates amid the 50’s were drugs like Valium, which had fewer side-effects and were less likely to kill you if you overdosed, which Marilyn Monroe unfortunately never got to learn.

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