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April 1, 2024
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Cancer Milestones
Criada
Jade Parker
⟶ Atualizado 31 jan 2019 ⟶
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Eventos
1979 TP53 gene discovered
1984 HER2 gene discovered
2001 First draft of the human genome is published
2002 BRAF gene faulty in more than half of melanoma cancers
2008 Whole genome sequenced of a woman with AML
2017 100,000 Genomes project launched
1994 BRAC1 tumor supressor gene cloned
1995 BRAC2 gene cloned
2017 72 new breast cancer gene variants discovered
1984 Link made between HPV and cervical carcinogenesis
1998 Trastuzumab approved for HER-2 positive breast cancer
1997 Rituximab approved for NHL
2006 HPV vaccine Gardasil approved
2010 First human-cancer treatment vaccine (sipuleucel-T) approved
2011 Ipilimumab approved for metastatic melanoma
2014 Pembrolizumab approved for advanced melanoma
1992 Paclitaxel approved for ovarian cancer
1989 VEGF discovered
1991 Angiostatin and endostatin discovered
2017 First CAR-T treatment Kymriah approved
2017 Keytruda approved
1950 Cigarette smoking identified as an important factor in the development of lung cancer
1964 Epstein-Barr virus linked to human cancer
2018 Personalized immunotherapy leads to complete response in metastatic breast cancer patient
2018 Blood test detects eight cancer types
2018 TAILORx findings presented at ASCO 2018
2018 Nivolumab, ipilimumab combo succeeds in CheckMate-227 trial
2018 US FDA approves larotrectinib
