15 ago 1517 ano - Portuguese merchant Fernão Pires de Andrade meets Ming Dynasty Chinese officials through an interpreter, at the Pearl River estuary and lands, at what is now in the jurisdiction of Hong Kong. Although the first European trade expeditions to China took place in 1513 and 1516 by Jorge Álvares and Rafael Perestrello, respectively, Andrade's mission is the first official diplomatic mission of a European power to China, commissioned by a ruler of Europe (Manuel I of Portugal) (Linha do tempo)