1 jan 1621 ano - Robert Burton published his "Anatomy of Melancholy"

Descrição:

- examined the connection between body and mind and the effect of mental trauma on the body (ie. appetite, sleep, appearance etc.)

- gave a list of triggers for his experience of extreme melancholia
(some highly traumatic but also the grim state of world affairs) could lead to a maddened despair

- solemn tone and his endeavour to prove indisputable facts by weighty quotations were ridiculed by Laurence Sterne in Tristram Shandy

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