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Wijnand Schravesande
⟶ è stato aggiornato 7 feb 2018 ⟶
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Eventi
Gregor mendel uses peas to figure out the fundamental principles of heredity
Friedrich miescher isolates DNA, in the form of chormatin
Francis Crick and James watson Publish the structure of DNA as a double helix
Robert Holley and coworkers sequence yeast tRNA
Ray Wu uses primer extension to read a short sequence of DNA for the first time
Walter Fiers Sequences first whole gene - coding for a MS2 virus protein
Walter Gilbert and Allan Maxam develop way to sequence DNA using chemicals to cut DNA at certain bases
Frederick Sanger introduces plus and minus method for DNA sequencing using gels to seperate newly synthesized DNA by size
Frederick Sanger Establishes dideoxy sequencing - uses it to sequence genome of bacteriophage ox174
Fritz Pohl develops non-radioactive sequencing platform
Leroy Hood and ABI develop first semi-automated DNA sequencing machines
First bacteria gets its genome sequenced: H. influenza
Mostafa Ronaghi introduces pyrosequencing, a next-generation "sequencing by synthesis" method ABI introduces introduces first commercial sequencing using capillary electrophoresis S. cerevesiae genome is sequenced
Solexa develops sequencing-by-synthesis method that uses fluorescent dues C. elegans genome is sequenced
First human chromosome 22 is sequenced
Complete mouse genome is published
The 454 system based on pyrosequencing, becomes the first next-generation sequencer to come on the market
A. thaliana and D. melanogaster genomes are sequenced
Human genome project publishes first draft human genome sequence, final sequence in 2003
Illumina buys solexa for $600 million SOLiD system, which uses sequencing by ligation, is launched
Whole DNA sequence of a cancer is decoded for the first time
Third generation sequencing with single molecule fluorescent technology is launched with helicos sequencer
Pacific Biosciences launches first commercial product - Pabio RS - based on single molecule real time technology
Oxford Nanopore technologies commercializes nanopore sequencing
Era of bioinformatics analysis and personalised medicine