1 janv. 1932 - Magic Bullets: Prontosil

Description:

In 1932, Gerhard Domagk tried to use prontosil, a red dye, in a series of tests on mice, and found that it had an effect on the bacteria that caused blood poisoning. In 1935, when Domagk's daughter pricked her finger on an infected needle and got severe blood poisoning, he gave her a large dose of prontosil. Even he had not tested it on humans before, his daughter recovered from the disease, meaning he had found the second magic bullet.
The active ingredient of prontosil was identified as a sulphonamide. A whole group of drugs based on sulphonamides followed, including M&B 693, which worked on pneumonia without turning you red. Unfortunately, more serious side effects were discovered, such as liver and kidney damage.

The discovery of magic bullets showed that synthetic, targeted treatments for specific disease were possible. Since Paul Ehrlich's first discovery, a huge pharmaceutical industry has grown, dedicated to the research and production of new treatments.

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