1 janv. 1911 - Magic Bullets: Salvarsan 606

Description:

During the late 1800s, Paul Ehrlich spent hours researching bacteria and was fascinated by how the body created antibodies that killed bacteria but did not harm anything else. In 1889, Ehrlich set out to find chemicals that could act as synthetic antibodies - or magic bullets - to defend the body against bacteria.
In 1905, the bacterium that causes the sexually transmitted disease syphilis was identified. Ehrlich and his team decided to search for an arsenic compound that was a magic bullet for syphilis, hoping it would target the bacteria without poisoning the rest of the body. Over 600 compounds were tried, but none seemed to work.
In 1909, Sahachiro Hata joined the team. He rechecked the results and saw that number 606 actually appeared to work. It was first used on a human in 1911 under the trade name Salvarsan 606.

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