26 avr. 2016 - HHIP found to be epigenetically silenced in lung adenocarcinomas. Overexpression of HHIP blocked HH activation - suggests silencing of HHIP is critical in potentiating HH activation and maintaining cell survival under stress conditions.

Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma.

3 oct. 2018

307

26 avr. 2016

Maintenaint

~ Il y a 9 ans et 5 mois

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