9 Jul 2010 Jahr - > BEST 1 (504 participants) Primary objectives: safety and acceptability Result: 1. 501/ 504 participants successfully swallowed the Cytosponge 2. For ≥1cm circumferential BE: sensitivity = 73.3%, specificity = 93.8% 3. For ≥ 2cm circumferential BE (clinically relevant): sensitivity = 90.0%, specificity = 93.5% Conclusion: procedure is safe; patients find it acceptable; lab results are promising.

Beschreibung:

Primary objectives: feasibility in primary care, safety, acceptability
Study design: prospective cohort study
Participants: 504 patients aged 50-70 years old with previous prescription for an acid suppressant.
Method: Cytosponge compared with gastroscopy
Data collection time: May 2008 to December 2009
Limitations: most participants reported low level of anxiety before the test
Funding: This research was supported by the Medical Research Council development gap fund, NIHR School for Primary Care Research, BD Diagnostics, Cambridge Experimental Cancer Medicine Centre, and the National Institute for Health Research Cambridge Biomedical Research Centre. Surepath preservative fluid was a gift from BD Diagnostics.

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