1 Jan 1500 Jahr - 1500: According to several accounts from the 1500s, smallpox inoculation was practiced in China and India (one is referred to in volume 6 of Joseph Needham's Science and Civilization in China). Glynn & Glynn, in The Life and Death of Smallpox, note that in the late 1600s Emperor K'ang Hsi, had his children inoculated. That method involved grinding up smallpox scabs and blowing the matter into nostril. It is difficult to pinpoint when the practice began, as some sources claim dates as early as 200 BCE.
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