1 Jul 1881 Jahr - Wernicke-Korsakoff syndrome

Beschreibung:

thiamine (vitamin B1) deficiency, and is typically seen in alcoholics.
It is named after 2:

Carl Wernicke: German neurologist and psychiatrist (1848-1905)
Sergei Sergeievich Korsakoff: Russian neuropsychiatrist (1853-1900)

It was originally described as characterised by the triad of:

acute confusion
ataxia
ophthalmoplegia
Wernicke encephalopathy can evolve into the chronic form of thiamine deficiency known as Korsakoff psychosis, characterised by:
memory loss (global amnesia)
confabulation

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