26 Apr 2016 Jahr - HHIP found to be epigenetically silenced in
lung adenocarcinomas. Overexpression of
HHIP blocked HH activation - suggests
silencing of HHIP is critical in potentiating HH
activation and maintaining cell survival under
stress conditions.
Beschreibung:
Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma.
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